Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Pressure‐controlled versus volume‐controlled ventilation for acute respiratory failure due to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) Author(s): Chacko B, Peter JV, Tharyan P, John G, Jeyaseelan L Publisher or Source: Cochrane Database of Systematic Reviews Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: India Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) account for one‐quarter of cases of acute respiratory failure in intensive care units (ICUs). A third to half of patients will die in the ICU, in hospital or during follow‐up. Mechanical ventilation of people with ALI/ARDS allows time for the lungs to heal, but ventilation is invasive and can result in lung injury. It is uncertain whether ventilator‐related injury would be reduced if pressure delivered by the ventilator with each breath is controlled, or whether the volume of air delivered by each breath is limited. Objectives To compare pressure‐controlled ventilation (PCV) versus volume‐controlled ventilation (VCV) in adults with ALI/ARDS to determine whether PCV reduces in‐hospital mortality and morbidity in intubated and ventilated adults. Search methods In October 2014, we searched the Cochrane Central Register of Controlled Trials (CENTRAL) (2014, Isssue 9), MEDLINE (1950 to 1 October 2014), EMBASE (1980 to 1 October 2014), the Latin American Caribbean Health Sciences Literature (LILACS) (1994 to 1 October 2014) and Science Citation Index‐Expanded (SCI‐EXPANDED) at the Institute for Scientific Information (ISI) Web of Science (1990 to 1 October 2014), as well as regional databases, clinical trials registries, conference proceedings and reference lists. Selection criteria Randomized controlled trials (RCTs) and quasi‐RCTs (irrespective of language or publication status) of adults with a diagnosis of acute respiratory failure or acute on chronic respiratory failure and fulfilling the criteria for ALI/ARDS as defined by the American‐European Consensus Conference who were admitted to an ICU for invasive mechanical ventilation, comparing pressure‐controlled or pressure‐controlled inverse‐ratio ventilation, or an equivalent pressure‐controlled mode (PCV), versus volume‐controlled ventilation, or an equivalent volume‐controlled mode (VCV). Data collection and analysis Two review authors independently screened and selected trials, assessed risk of bias and extracted data. We sought clarification from trial authors when needed. We pooled risk ratios (RRs) for dichotomous data and mean differences (MDs) for continuous data with their 95% confidence intervals (CIs) using a random‐effects model. We assessed overall evidence quality using the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach. Main results We included three RCTs that randomly assigned a total of 1089 participants recruited from 43 ICUs in Australia, Canada, Saudi Arabia, Spain and the USA. Risk of bias of the included studies was low. Only data for mortality and barotrauma could be combined in the meta‐analysis. We downgraded the quality of evidence for the three mortality outcomes on the basis of serious imprecision around the effect estimates. For mortality in hospital, the RR with PCV compared with VCV was 0.83 (95% CI 0.67 to 1.02; three trials, 1089 participants; moderate‐quality evidence), and for mortality in the ICU, the RR with PCV compared with VCV was 0.84 (95% CI 0.71 to 0.99; two trials, 1062 participants; moderate‐quality evidence). One study provided no evidence of clear benefit with the ventilatory mode for mortality at 28 days (RR 0.88, 95% CI 0.73 to 1.06; 983 participants; moderate‐quality evidence). The difference in effect on barotrauma between PCV and VCV was uncertain as the result of imprecision and different co‐interventions used in the studies (RR 1.24, 95% CI 0.87 to 1.77; two trials, 1062 participants; low‐quality evidence). Data from one trial with 983 participants for the mean duration of ventilation, and from another trial with 78 participants for the mean number of extrapulmonary organ failures that developed with PCV or VCV, were skewed. None of the trials reported on infection during ventilation or quality of life after discharge. Authors' conclusions Currently available data from RCTs are insufficient to confirm or refute whether pressure‐controlled or volume‐controlled ventilation offers any advantage for people with acute respiratory failure due to acute lung injury or acute respiratory distress syndrome. More studies including a larger number of people given PCV and VCV may provide reliable evidence on which more firm conclusions can be based. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: STRESS MANAGEMENT INTERVENTION TO PREVENT POST–INTENSIVE CARE SYNDROME–FAMILY IN PATIENTS’ SPOUSES Author(s): Cairns, P.L., Buck, H.G., Kip, K.E., Rodriguez, C.S., Liang, Z., and Munro, C.L. Publisher or Source: American Journal of Critical Care Nurses Type of Media: Medical Journal Media Originally for: General Medical Professionals, Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States Primary Focus of Media: Post Intensive Care Syndrome for Families (PICS-F) COVID-19 Related: No Description: Post–intensive care syndrome–family (PICS-F) refers to acute and chronic psychological effects of critical care on family members of patients in intensive care units (ICUs). Evidence suggests that increased distress during the ICU stay increases risk of PICS-F. Sensation Awareness Focused Training (SAF-T) is a new, promising ˉ stress management intervention, but the feasibility of such training during the ICU stay for family caregivers who are acting as the surrogate decision-maker for patients who are undergoing mechanical ventilation is unknown. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Factors associated with bronchiolitis obliterans syndrome and chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation Author(s): Lee Gazourian, Angela J. Rogers, Ruby Ibanga, Gerald L. Weinhouse, Victor Pinto-Plata, Jerome Ritz, Robert J. Soiffer, Joseph H. Antin, George R. Washko, Rebecca M. Baron, and Vincent T. Ho3 Publisher or Source: American Journal of Hematology Type of Media: Medical Research Media Originally for: Critical Care Physicians, Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Bronchiolitis obliterans syndrome (BOS) is a form of chronic graft vs. host disease (cGVHD) and a highly morbid pulmonary complication after allogeneic hematopoietic stem cell transplantation (HSCT). We assessed the prevalence and risk factors for BOS and cGVHD in a cohort of HSCT recipients, including those who received reduced intensity conditioning (RIC) HSCT. Between January 1, 2000 and June 30, 2010, all patients who underwent allogeneic HSCT at our institution (n 5 1854) were retrospectively screened for the development of BOS by PFT criteria. We matched the BOS cases with two groups of control patients: (1) patients who had concurrent cGVHD without BOS and (2) those who developed neither cGVHD nor BOS. Comparisons between BOS patients and controls were conducted using t-test or Fisher’s exact tests. Multivariate regression analysis was performed to examine factors associated with BOS diagnosis. All statistical analyses were performed using SAS 9.2. We identified 89 patients (4.8%) meeting diagnostic criteria for BOS at a median time of 491 days (range: 48–2067) after HSCT. Eighty-six (97%) of our BOS cohort had extra-pulmonary cGVHD. In multivariate analysis compared to patients without cGVHD, patients who received busulfan-based conditioning, had unrelated donors, and had female donors were significantly more likely to develop BOS, while ATG administration was associated with a lower risk of BOS. Our novel results suggest that busulfan conditioning, even in RIC transplantation, could be an important risk factor for BOS and cGVHD. Am. J. Hematol. 89:404–409, 2014. VC 2013 Wiley Periodicals, Inc. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Management of moderate and severe alcohol withdrawal syndromes Author(s): Robert S Hoffman, MD; and Gerald L Weinhouse, MD Publisher or Source: UpToDate Type of Media: Medical Journal Media Originally for: Critical Care Physicians, General Public, General Medical Professionals, Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Alcoholism is such a common condition that virtually every clinician is confronted with its complications. There are an estimated 8 million alcohol dependent people in the United States. Approximately 500,000 episodes of withdrawal severe enough to require pharmacologic treatment occur each year The in-patient management of syndromes associated with moderate and severe alcohol withdrawal is reviewed here. The ambulatory management of mild alcohol withdrawal, the initial diagnosis and treatment of alcohol dependence, and specific conditions due to alcohol-related organ damage (eg, cirrhosis, pancreatitis) are discussed elsewhere. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Several Delhi hospitals report Covid complication in children: multi inflammatory syndrome Author(s): Sukrita Baruah Publisher or Source: The Indian Express Type of Media: Newspaper Article Media Originally for: General Public,General Medical Professionals Country of Origin: India Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: Over the last month, several hospitals across Delhi have reported cases of multi inflammatory syndrome in children (MIS-C) as a post-Covid complication, though city pediatricians emphasise that affected children have responded well to treatment. According to the Lancet, the factors that trigger the condition are not yet known but it is thought to be a rare immune overreaction that occurs approximately four to six weeks after a mild or asymptomatic SARS-CoV-2 infection. The symptoms include fever for three days, rash, eye infection and gastrointestinal symptoms like diarrhoea, stomach-ache and nausea. In very rare cases, the condition can lead to multi-organ failure. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Reappraisal of visiting policies and procedures of patient’s family information in 188 French ICUs: a report of the Outcomerea Research Group Author(s): MaitéGarrouste‑Orgeas, IsabelleVinatier, AlexisTabah, BenoitMisset andJean‑FrançoisTimsit Publisher or Source: Annals of Intensive Care Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: France Primary Focus of Media: Post Intensive Care Syndrome for Families (PICS-F) COVID-19 Related: No Description: Background:The relatives of intensive care unit (ICU) patients must cope with both the severity of illness of their loved one and the unfamiliar and stressful ICU environment. This hardship may lead to post‑intensive care syndrome. French guidelines provide recommendations on welcoming and informing families of ICU patients. We questioned whether and how they are applied 5years after their publication. Methods:We conducted a large survey among French ICUs to evaluate their visiting policies and how information was provided to patient’s family. A questionnaire was built up by intensivists and nurses. French ICUs were solicited, and the questionnaire was sent to all participating ICUs, for being filled in by the unit medical and/or nursing head. Data regarding the hospital and ICU characteristics, the visiting policy and procedures, and the management of family information were collected. Results:Among the 289 French ICUs, 188 (65%) participated. Most ICUs have a waiting room 118/188 (62.8%) and a dedicated room for meeting the family 152/188 (80.8%). Of the 188 ICUs, 45 (23.9%) were opened on a 24‑h‑a‑day basis. In the remaining ICUs, the time period allowed for visits was 4.75±1.83h (median 5h). In ICUs where visit‑ing restrictions were reported, open visiting was allowed for end‑of‑life situations in 107/143 (74.8%). Children are allowed to visit a patientin 164/188 (87.2%) regardless of their age in 97/164 (59.1%) of ICUs. Families received an information leaflet in 168/188 (89.3%). Information was provided to families through structured meetings in 149/188 (79.2%) of ICUs at patient admission with participation of nurses and nursing assistants in 133/188 (70.4%) and 55/188 (29.2%), respectively. Information delivered to the family was reported in the patient chart by only 111/188 ICUs (59%). Participation in care was infrequent. Conclusions:Although French ICUs do not follow the consensus recommendations, slow progress exists com‑pared to previous reports. Implementation of these recommendations is largely needed to offer better welcome and information improvement. Further studies on that topic would enable evaluating remaining obstacles and increasing caregivers’ awareness, both critical for further progresses on that topic. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Long covid could be four different syndromes, review suggests Author(s): Elisabeth Mahase Publisher or Source: The BMJ Type of Media: Medical Journal Media Originally for: Critical Care Physicians,General Medical Professionals,Nurses and/or Other Critical Care Medical Professionals Country of Origin: United Kingdom of Great Britain and Northern Ireland (the) Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: Long covid, the name commonly used to explainlasting effects of covid-19, may actually be fourdifferent syndromes, according to a review by theNational Institute for Health Research (NIHR). A team of researchers and doctors reviewed currentevidence and interviewed post-hospitalised andnon-hospitalised patients and reported that longcovid did not seem to fit as one syndrome. Theysuggested that people experiencing long term effectsof covid-19 may have different syndromes such aspost-intensive care syndrome, post-viral fatiguesyndrome, and long term covid syndrome To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Critical care rehabilitation & Post Intensive Care Syndrome Author(s): Andrea Attorri PT, DPT Publisher or Source: American Association of Critical-Care Nurses Type of Media: PowerPoint Media Originally for: Critical Care Physicians, General Medical Professionals, Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: No Description: The power point main points: PICS is a big deal for patients and families and it does not go away as soon as they leave the ICU Awareness and advocacy are crucial PICS is going to be an on-going research point in the next decade, with several large RCT’s and clinical practice guidelines in review process to be published *Survival by itself is not a patient-centered endpoint* From a hospital metrics and bench-marking standpoint, surviving an ICU admission is typically where the data collection ends To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Does fast-track treatment lead to a decrease of intensive care unit and hospital length of stay in coronary artery bypass patients: a meta-regression of randomized clinical trials Author(s): University of York-the Centre for Reviews and Dissemination Publisher or Source: Database of Abstracts of Reviews of Effects (DARE) Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: United Kingdom of Great Britain and Northern Ireland (the) Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: The review assessed whether fast-track treatments for adults at low risk of complications after coronary artery bypass surgery reduce the length of stay in hospital. The authors concluded that a protocol for early tracheal extubation appears essential. The authors did not provide sufficient information about the included studies to justify their conclusions. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: After ICU: ‘Fraternity of People Who Are Struggling’ Author(s): Kathleen Ronan, Annie Johnson, Carla Sevin, Gerald Weinhouse, Dale Needham, Jim Jackson Publisher or Source: WebMD Type of Media: Newspaper Article Media Originally for: General Public Country of Origin: United States Primary Focus of Media: PICS and PICS-F COVID-19 Related: No Description: Researchers are still trying to understand everything that Ronan and other COVID-19 patients need to let them move on with their lives after being in the ICU. Mysteries abound, but the groundwork laid by Sevin, Needham, Weinhouse, and others has provided a solid foundation on which to build. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Intensive insulin therapy in hospitalized patients: a systematic review Author(s): University of York-the Centre for Reviews and Dissemination Publisher or Source: Database of Abstracts of Reviews of Effects (DARE) Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: United Kingdom of Great Britain and Northern Ireland (the) Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: This review concluded that intensive insulin therapy did not reduce mortality or improve health outcomes in hospitalised patients, but that it was associated with increased risk of severe hypoglycaemia. The authors' conclusions reflected the evidence presented, but in view of the potential for language bias and the clinical variation between trials, the conclusions should be viewed with caution. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Understanding Your ICU Stay Author(s): Society of Critical Care Medicine Publisher or Source: Society of Critical Care Medicine Type of Media: Medical Professional Education Media Originally for: Former ICU Patients, Former ICU Patients' Family Members, Friends or Caregivers Country of Origin: United States Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: No Description: The book explains to the family of the patients in the ICU what to expect and provides information to them so that they can better informed decision. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.