Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia: Systematic Review and Individual Patient Data Meta analysis Author(s): Matthias Briel, Simone M C Spoorenberg, Dominic Snijders, Antoni Torres, Silvia Fernandez-Serrano, G Umberto Meduri, Albert Gabarrús, Claudine A Blum, Marco Confalonieri, Benjamin Kasenda, Reed AC Siemieniuk, Wim Boersma, Willem Jan W Bos, Mirjam Christ-Crain, Ovidius Study Group, Capisce Study Group and STEP Study Group Publisher or Source: Clinical Infectious Diseases Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: Canada Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Background Our aim was to evaluate the benefits and harms of adjunctive corticosteroids in adults hospitalized with community-acquired pneumonia (CAP) using individual patient data from randomized, placebo-controlled trials and to explore subgroup differences. Methods We systematically searched Medline, Embase, Cochrane Central, and trial registers (all through July 2017). Data from 1506 individual patients in 6 trials were analyzed using uniform outcome definitions. We investigated prespecified effect modifiers using multivariable hierarchical regression, adjusting for pneumonia severity, age, and clustering effects. Results Within 30 days of randomization, 37 of 748 patients (5.0%) assigned to corticosteroids and 45 of 758 patients (5.9%) assigned to placebo died (adjusted odds ratio [aOR], 0.75; 95% confidence interval [CI], .46 to 1.21; P = .24). Time to clinical stability and length of hospital stay were reduced by approximately 1 day with corticosteroids (–1.03 days; 95% CI, –1.62 to –.43; P = .001 and –1.15 days; 95% CI, –1.75 to –.55; P < .001, respectively). More patients with corticosteroids had hyperglycemia (160 [22.1%] vs 88 [12.0%]; aOR, 2.15; 95% CI, 1.60 to 2.90; P < .001) and CAP-related rehospitalization (33 [5.0%] vs 18 [2.7%]; aOR, 1.85; 95% CI, 1.03 to 3.32; P = .04). We did not find significant effect modification by CAP severity or degree of inflammation. Conclusions Adjunct corticosteroids for patients hospitalized with CAP reduce time to clinical stability and length of hospital stay by approximately 1 day without a significant effect on overall mortality but with an increased risk for CAP–related rehospitalization and hyperglycemia. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Italy reports 502 coronavirus deaths on Tuesday, 20,396 new cases Author(s): Cristina Carlevaro, Gianluca Semeraro Publisher or Source: Reuters Type of Media: Newspaper Article Media Originally for: General Public Country of Origin: Italy Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: Yes Description: MILAN (Reuters) -Italy reported 502 coronavirus-related deaths on Tuesday against 354 the day before, the health ministry said, while the daily tally of new infections rose to 20,396 from 15,267 the day before. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Liberal versus conservative fluid therapy in adults and children with sepsis or septic shock Author(s): Li D, Li X, Cui W, Shen H, Zhu H, Xia Y Publisher or Source: Cochrane Database of Systematic Reviews Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: United States Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Review question We aimed to investigate whether liberal fluid therapy can lead to more beneficial or harmful effects compared to conservative fluid therapy for adults and children with severe sepsis or septic shock. We mainly evaluated the different effects of these two interventions on risk of death and occurrence of adverse events. Background Sepsis and septic shock are complications of infection. Patients in the intensive care unit (ICU) are more likely than others to be affected by this condition. Once affected, patients experience organ dysfunction, which in some cases may lead to death. Fluid therapy is often used as an important intervention for initial treatment of sepsis in adults and children. Results We searched the electronic databases on 16 January 2018. We identified no adult trials that met our inclusion criteria. We included three trials involving 3402 children. We identified three 'ongoing' trials that have not yet been published. Pooled results from two trials (involving 3288 children) show that liberal fluid therapy may increase risk of in‐hospital death by 38%, and risk of death at four‐week follow‐up by 39%. This means that for every 34 children receiving fluid therapy, one more in‐hospital death will occur in the liberal fluid therapy group than in the conservative fluid therapy group. Similarly, at four‐week follow‐up, one more death will occur in the liberal fluid therapy group than in the conservative fluid therapy group for every 29 children receiving fluid therapy. One small study reported inconclusive results on risk of in‐hospital death. We are uncertain whether there is a difference in adverse events (i.e. hepatomegaly, need for ventilation, allergic reaction, and neurological sequelae) between patients receiving liberal versus conservative fluid therapy. One trial (involving 101 children) reported that conservative fluid therapy can shorten ICU stay and the duration of ventilation. However, we have very little confidence in this finding owing to the small sample size. We found no studies investigating adults with sepsis or septic shock. Conclusion Low‐ to high‐quality evidence shows that liberal fluid therapy may increase the death rate for children with sepsis or septic shock. Except for this finding, we are uncertain about the effects of liberal versus conservative fluid therapy on the risk of adverse events. We are also uncertain about the effects of these two interventions for adults with sepsis or septic shock due to lack of data. Future trials focusing on adult sepsis or septic shock in other settings, with a wider range of pathogens, are expected. Once published and assessed, the three 'ongoing' studies identified may alter the conclusions of this review. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Diprivan 2% emulsion for injection Author(s): Electronic Medicines Compendium - EMC Publisher or Source: electronic Medicines compendium Type of Media: Medical Professional Education Media Originally for: Critical Care Physicians Country of Origin: Ireland Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: New interaction information added includes reports of profound hypertension following anaesthetic with propofol in patients treated with rifampicin; a possible requirement for dose reduction in patients taking valproate; and information on use with other CNS depressants. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Uncovering the “Silent” Epidemic of Psychological Distress in Critical Care Healthcare Professionals Author(s): Marc Moss, M.D.; Roger S. Mitchell Publisher or Source: American Thoracic Society Type of Media: PowerPoint Media Originally for: Critical Care Physicians, General Medical Professionals, Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States Primary Focus of Media: Post Traumatic Stress Disorder (PTSD) COVID-19 Related: No Description: Outline: • What is different in the intensive care unit (ICU) • Highlight ICU nurses • Specific ICU-related consequences on well-being • Potential interventions • My thoughts on future directions To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: ICU Treatment Linked to PTSD Symptoms Author(s): Jeff Levine Publisher or Source: WebMD Type of Media: One-Pager Media Originally for: General Public Country of Origin: United States Primary Focus of Media: Post Traumatic Stress Disorder (PTSD) COVID-19 Related: No Description: A new study finds that treatment in the intensive care unit has a unique set of terrors -- painful enough to be a precipitating factor in the onset of posttraumatic stress disorder (PTSD). The conclusion comes from a German study of patients who spent at least one month in the intensive care unit (ICU) at the University of Munich and were evaluated for PTSD up to three years later. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Effectiveness of dexmedetomidine versus propofol on extubation times, length of stay and mortality rates in adult cardiac surgery patients: a systematic review and meta-analysis Author(s): John Nguyen , and Noel Nacpil Publisher or Source: Joanna Briggs Institute Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: United Kingdom of Great Britain and Northern Ireland (the) Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Objective: To determine the effects of dexmedetomidine versus propofol on extubation time, intensive care unit (ICU) length of stay, total hospital length of stay and in-hospital mortality rates in cardiac surgery patients. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Why PTSD May Plague Many Hospitalized Covid-19 Survivors Author(s): Claire Bugos Publisher or Source: Smithsonian Type of Media: Magazine Article Media Originally for: General Public Country of Origin: United States of America (the) Primary Focus of Media: Post Traumatic Stress Disorder COVID-19 Related: Yes Description: While neuropsychologists Erin Kaseda and Andrew Levine were researching the possibility of hospitalized Covid-19 patients developing post-traumatic stress disorder (PTSD), they heard reports of patients experiencing vivid hallucinations. Restrained by ventilators and catheters, delirious from medication and sedatives and confused by the changing cast of medical professionals cycling through the ward, intensive care unit (ICU) patients are especially prone to trauma. For Covid-19 ICU patients, a combination of factors, including side effects of medication, oxygenation issues and possibly the virus itself, can cause delirium and semi-consciousness during their hospital stay. Kaseda says as these patients slip in and out of consciousness, they may visualize doctors wheeling their bodies to a morgue or see violent imagery of their families dying. Such instances, though imagined, can cause trauma that may lead to PTSD in patients long after they have physically recovered from Covid-19. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Developing and setting up a patient and relatives intensive care support group Author(s): Maureen Peskett and Peter Gibb Publisher or Source: British Association of Critical Care Nurses Type of Media: Medical Journal Media Originally for: Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States Primary Focus of Media: PICS and PICS-F COVID-19 Related: No Description: Aim:The purpose of this article was to highlight the need to provide support for patients and relatives following critical illness and discharge from hospital and how this can be improved through the establishment of user support groups. Background:Critical illness predisposes patients to extended physical and psychological ill health with the potential for a reduced quality of life. The authors’ personal experience, patient feedback and current literature suggested that there was a need for further support during their recovery. Methods:Building on an existing formal follow-up service, Intensive Care Unit (ICU) Support Team for Ex-Patients established a patient-centred forum, where patients and relatives could share experiences with others who had also been through critical illness by holding drop-in sessions. Feedback from those attending these flexible and informal sessions indicates that support was needed and that patients and families have found benefit in sharing experiences with others who can empathise, having been through critical illness themselves. Conclusions:Our experience has shown there is a need that can be met simply with minimal investment of time and funding but that addresses a gap in patient support that otherwise goes unmet. Although this was a service development in one local area, it could be adapted to ICU patients and relatives more widely To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Psychosocial outcomes in informal caregivers of the critically ill: a systematic review Author(s): Kimberley J Haines , Linda Denehy, Elizabeth H Skinner, Stephen Warrillow, Sue Berney Publisher or Source: Critical Care Medicine Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: Australia Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: The objective of the review was to evaluate and synthesize the prevalence, risk factors, and trajectory of psychosocial morbidity in informal caregivers of critical care survivors. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Dynamics of Critical Care Conference 2019 Author(s): Canadian Association of Critical Care Nurses Publisher or Source: Canadian Association of Critical Care Nurses (CACCN) Type of Media: Brochure Media Originally for: Nurses and/or Other Critical Care Medical Professionals Country of Origin: Canada Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: No Description: Dynamics is the annual national convention and product exhibition of the Canadian Association of Critical Care Nurses (CACCN). Diverse programming allows participants to choose from a broad selection of evidence-based topics that are geared to enhancing clinical practice, leadership, education, and research. With paediatric and adult critical care opportunities provided, participants design educational agendas to meet their own unique needs. Dynamics brings colleagues together from coast to coast, to share ideas and experiences. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Procalcitonin testing for diagnosing and monitoring sepsis (ADVIA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive Kryptor assay, Elecsys BRAHMS PCT assay, LIAISON BRAHMS PCT assay and VIDAS BRAHMS PCT assay) - guidance (DG18) Author(s): National Institute for Health and Care Excellence - NICE Publisher or Source: National Institute for Health and Care Excellence - NICE Type of Media: Medical Professional Education Media Originally for: Critical Care Physicians, General Medical Professionals, Nurses and/or Other Critical Care Medical Professionals Country of Origin: United Kingdom Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: NICE has assessed the procalcitonin tests (ADVIA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive Kryptor assay, Elecsys BRAHMS PCT assay, LIAISON BRAHMS PCT assay and VIDAS BRAHMS PCT assay) to help the NHS decide whether to use these products. Procalcitonin is released into the bloodstream when there is a bacterial infection in the body and high levels can show that a person has a serious bacterial infection. Procalcitonin tests measure the amount of procalcitonin in the blood, and the results can help doctors to diagnose bacterial infection and decide about starting or stopping antibiotic treatment. There was not enough evidence to recommend that these tests are used in the NHS. But NICE has recommended further research and data collection to show the impact of adding procalcitonin testing to standard clinical practice in the NHS. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.