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  • An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement:Responding to Requests for Potentially Inappropriate Treatments inIntensive Care Units

    Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement:Responding to Requests for Potentially Inappropriate Treatments inIntensive Care Units Author(s): Gabriel T. Bosslet, Thaddeus M. Pope, Gordon D. Rubenfeld, Bernard Lo, Robert D. Truog, Cynda H. Rushton,J. Randall Curtis, Dee W. Ford, Molly Osborne, Cheryl Misak, David H. Au, Elie Azoulay, Baruch Brody,Brenda G. Fahy, Jesse B. Hall, Jozef Kesecioglu, Alexander A. Kon, Kathleen O. Lindell, and Douglas B. White Publisher or Source: American Thoracic Society; American Association of Critical Care Nurses; American College of Chest Physicians; European Society of Intensive Care Medicine; Society of Critical Care Medicine Type of Media: Medical Journal Media Originally for: Critical Care Physicians,Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States of America (the) Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: The multisociety statement on responding to requests for potentially inappropriate treatments in intensive care units provides guidance for clinicians to prevent and manage disputes in patients with advanced critical illness. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

  • Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia: Systematic Review and Individual Patient Data Meta analysis

    Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia: Systematic Review and Individual Patient Data Meta analysis Author(s): Matthias Briel, Simone M C Spoorenberg, Dominic Snijders, Antoni Torres, Silvia Fernandez-Serrano, G Umberto Meduri, Albert Gabarrús, Claudine A Blum, Marco Confalonieri, Benjamin Kasenda, Reed AC Siemieniuk, Wim Boersma, Willem Jan W Bos, Mirjam Christ-Crain, Ovidius Study Group, Capisce Study Group and STEP Study Group Publisher or Source: Clinical Infectious Diseases Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: Canada Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Background Our aim was to evaluate the benefits and harms of adjunctive corticosteroids in adults hospitalized with community-acquired pneumonia (CAP) using individual patient data from randomized, placebo-controlled trials and to explore subgroup differences. Methods We systematically searched Medline, Embase, Cochrane Central, and trial registers (all through July 2017). Data from 1506 individual patients in 6 trials were analyzed using uniform outcome definitions. We investigated prespecified effect modifiers using multivariable hierarchical regression, adjusting for pneumonia severity, age, and clustering effects. Results Within 30 days of randomization, 37 of 748 patients (5.0%) assigned to corticosteroids and 45 of 758 patients (5.9%) assigned to placebo died (adjusted odds ratio [aOR], 0.75; 95% confidence interval [CI], .46 to 1.21; P = .24). Time to clinical stability and length of hospital stay were reduced by approximately 1 day with corticosteroids (–1.03 days; 95% CI, –1.62 to –.43; P = .001 and –1.15 days; 95% CI, –1.75 to –.55; P < .001, respectively). More patients with corticosteroids had hyperglycemia (160 [22.1%] vs 88 [12.0%]; aOR, 2.15; 95% CI, 1.60 to 2.90; P < .001) and CAP-related rehospitalization (33 [5.0%] vs 18 [2.7%]; aOR, 1.85; 95% CI, 1.03 to 3.32; P = .04). We did not find significant effect modification by CAP severity or degree of inflammation. Conclusions Adjunct corticosteroids for patients hospitalized with CAP reduce time to clinical stability and length of hospital stay by approximately 1 day without a significant effect on overall mortality but with an increased risk for CAP–related rehospitalization and hyperglycemia. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

  • Paediatric inflammatory multisystem syndrome temporally associated with COVID-19

    Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 Author(s): RA Berard, R Scuccimarri, EM Haddad, MP Morin, K Chan, NS Dahdah, BW McCrindle, VE Price, RS Yeung, RM Laxer, Acute Care Committee Publisher or Source: Canadian Paediatric Society Type of Media: Medical Professional Education Media Originally for: Critical Care Physicians Country of Origin: Canada Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: Yes Description: This practice point reviews the clinical presentation of paediatric multisystem inflammatory syndrome temporally associated with COVID-19 and investigations to conduct when considering this diagnosis. Potential treatment options and indications for subspecialty consultation or transfer to tertiary care are also described. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

  • The association between critical illness and changes in bone turnover in adults: a systematic review

    Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: The association between critical illness and changes in bone turnover in adults: a systematic review Author(s): N. Orford , C. Cattigan , S. L. Brennan , M. Kotowicz, J. Pasco, & D. J. Cooper Publisher or Source: Springer Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: Australia Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Summary Critical illness may lead to altered bone turnover and associated adverse health outcomes. This systematic review found moderate evidence for a positive association between critical illness and increased bone turnover. Prospective cohort studies that identify the extent and risk factors for critical illness related bone loss are required. Introduction Intensive care patients face health issues that extend beyond their critical illness and result in significant morbidity and mortality. Critical illness may result in altered bone turnover due to associated immobilisation, inflammation, exposure to medications that effect bone and calcium metabolism, and endocrine dysfunction. The aim of this study was to synthesise the existing evidence for altered bone turnover in adults admitted to intensive care. Methods A literature search using MEDLINE and EMBASE was performed from 1965 to March 2013. Reviewed studies investigated the relationship between critical illness and evidence of altered bone turnover (bone turnover markers, bone mineral density, or fracture). Studies were rated upon their methodological quality, and a best-evidence synthesis was used to summarise the results. Results Four cohort and seven case–control studies were identified for inclusion, of which five studies were rated as being of higher methodological quality. Ten of the studies measured bone turnover markers, and one study fracture rate. Findings were consistent across studies, and best-evidence analysis resulted in a conclusion that moderate evidence exists for an association between critical illness requiring admission to intensive care and altered bone turnover. Conclusion A positive association between critical illness requiring intensive care admission and bone turnover exists, although data are limited, and the risk factors and the nature of the relationship are not yet understood. Prospective cohort studies that identify risk factors and extent of critical illness related bone turnover changes are required. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

  • Chelsea physical assessment tool for evaluating functioning in post‐intensive care unit COVID‐19 patients

    Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Chelsea physical assessment tool for evaluating functioning in post‐intensive care unit COVID‐19 patients Author(s): Alessandro de Sire, MD; Esra Giray, MD; and Ozden Ozyemisci Taskiran, MD Publisher or Source: Journal of Medical Virology Type of Media: Medical Journal Media Originally for: Critical Care Physicians,General Medical Professionals,Nurses and/or Other Critical Care Medical Professionals Country of Origin: Italy Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: By this letter, we aimed to address the need of an adequate assessment of functional status in post‐intensive care unit (ICU) coronavirus disease 2019 (COVID‐19) patients. COVID‐19 patients are at risk for post intensive care syndrome, with an impaired functional status. Physical and Rehabilitation Medicine (PRM) physicians have to face both acute and post-acute COVID‐19 patients and provide them with an adequate respiratory and neuromotor rehabilitation plan. To date, specific assessment tools are warranted to provide information regarding COVID‐19 patients' functioning. Chelsea Critical Care Physical Assessment Tool (CPAx) is a bedside assessment tool specifically designed to assess function in post‐ICU patients and has demonstrated validity, reliability, and responsiveness in critical care population. Taken together, we retain that the CPAx, due to its characteristics, might be used by PRM physicians for assessing functioning in post‐ICU COVID‐19 patients. COVID‐19 pandemic has reached more than 96.2 million of cases and more than 2 million of deaths at the moment of writing, putting under heavy stress health systems worldwide, especially ICUs. COVID‐19 survivors are at risk for post intensive care syndrome, including ICU‐acquired weakness and a consequent impairment in terms of functioning. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

  • OHSU starting specialized program to help treat COVID-19 long-haulers

    Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: OHSU starting specialized program to help treat COVID-19 long-haulers Author(s): Morgan Romero Publisher or Source: KGW.com Type of Media: Newspaper Article Media Originally for: General Public Country of Origin: United States of America (the) Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: PORTLAND, Ore. — Millions of Americans survive COVID-19, but lingering symptoms can stay with them for months. At Oregon Health & Science University (OHSU), there's a new program to try to treat patients considered long-haulers. It's one of dozens that has opened, or will be opening, in the U.S., as reported by NBC News. So far, it's the only specialized post-COVID clinic we know of in the state of Oregon. OHSU is finalizing its Long COVID-19 Program, which it hopes to launch in about a month. It's a specialized, coordinated approach to care for Oregonians dealing with an illness that doesn't have a known cure, now labeled Post-Acute Sequelae of SARS-CoV-2 infection (PASC). To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

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PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

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