Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Pressure‐controlled versus volume‐controlled ventilation for acute respiratory failure due to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) Author(s): Chacko B, Peter JV, Tharyan P, John G, Jeyaseelan L Publisher or Source: Cochrane Database of Systematic Reviews Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: India Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) account for one‐quarter of cases of acute respiratory failure in intensive care units (ICUs). A third to half of patients will die in the ICU, in hospital or during follow‐up. Mechanical ventilation of people with ALI/ARDS allows time for the lungs to heal, but ventilation is invasive and can result in lung injury. It is uncertain whether ventilator‐related injury would be reduced if pressure delivered by the ventilator with each breath is controlled, or whether the volume of air delivered by each breath is limited. Objectives To compare pressure‐controlled ventilation (PCV) versus volume‐controlled ventilation (VCV) in adults with ALI/ARDS to determine whether PCV reduces in‐hospital mortality and morbidity in intubated and ventilated adults. Search methods In October 2014, we searched the Cochrane Central Register of Controlled Trials (CENTRAL) (2014, Isssue 9), MEDLINE (1950 to 1 October 2014), EMBASE (1980 to 1 October 2014), the Latin American Caribbean Health Sciences Literature (LILACS) (1994 to 1 October 2014) and Science Citation Index‐Expanded (SCI‐EXPANDED) at the Institute for Scientific Information (ISI) Web of Science (1990 to 1 October 2014), as well as regional databases, clinical trials registries, conference proceedings and reference lists. Selection criteria Randomized controlled trials (RCTs) and quasi‐RCTs (irrespective of language or publication status) of adults with a diagnosis of acute respiratory failure or acute on chronic respiratory failure and fulfilling the criteria for ALI/ARDS as defined by the American‐European Consensus Conference who were admitted to an ICU for invasive mechanical ventilation, comparing pressure‐controlled or pressure‐controlled inverse‐ratio ventilation, or an equivalent pressure‐controlled mode (PCV), versus volume‐controlled ventilation, or an equivalent volume‐controlled mode (VCV). Data collection and analysis Two review authors independently screened and selected trials, assessed risk of bias and extracted data. We sought clarification from trial authors when needed. We pooled risk ratios (RRs) for dichotomous data and mean differences (MDs) for continuous data with their 95% confidence intervals (CIs) using a random‐effects model. We assessed overall evidence quality using the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach. Main results We included three RCTs that randomly assigned a total of 1089 participants recruited from 43 ICUs in Australia, Canada, Saudi Arabia, Spain and the USA. Risk of bias of the included studies was low. Only data for mortality and barotrauma could be combined in the meta‐analysis. We downgraded the quality of evidence for the three mortality outcomes on the basis of serious imprecision around the effect estimates. For mortality in hospital, the RR with PCV compared with VCV was 0.83 (95% CI 0.67 to 1.02; three trials, 1089 participants; moderate‐quality evidence), and for mortality in the ICU, the RR with PCV compared with VCV was 0.84 (95% CI 0.71 to 0.99; two trials, 1062 participants; moderate‐quality evidence). One study provided no evidence of clear benefit with the ventilatory mode for mortality at 28 days (RR 0.88, 95% CI 0.73 to 1.06; 983 participants; moderate‐quality evidence). The difference in effect on barotrauma between PCV and VCV was uncertain as the result of imprecision and different co‐interventions used in the studies (RR 1.24, 95% CI 0.87 to 1.77; two trials, 1062 participants; low‐quality evidence). Data from one trial with 983 participants for the mean duration of ventilation, and from another trial with 78 participants for the mean number of extrapulmonary organ failures that developed with PCV or VCV, were skewed. None of the trials reported on infection during ventilation or quality of life after discharge. Authors' conclusions Currently available data from RCTs are insufficient to confirm or refute whether pressure‐controlled or volume‐controlled ventilation offers any advantage for people with acute respiratory failure due to acute lung injury or acute respiratory distress syndrome. More studies including a larger number of people given PCV and VCV may provide reliable evidence on which more firm conclusions can be based. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Long covid: How to define it and how to manage it Author(s): Nikki Nabavi Publisher or Source: BMJ Type of Media: Medical Journal Media Originally for: Critical Care Physicians,General Medical Professionals,Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States of America (the) Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: On 3 September The BMJ hosted an online webinar on the diagnosis, management, and prognosis of “long covid.” An expert panel discussed its symptoms, course, and character and suggested strategies for managing it. Nikki Nabavi reports To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Coping With the “Long-Haul” of COVID-19: More Research, Treatments Needed Author(s): Tori Rodriguez, MA, LPC, AHC Publisher or Source: Pulmonology Advisor Type of Media: Magazine Article Media Originally for: Critical Care Physicians,General Public,General Medical Professionals Country of Origin: United States of America (the) Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: As the 1-year mark of the COVID-19 pandemic approaches, individuals with enduring impairment have become a focus of increasing attention. The term “long COVID” has been used to refer to the estimated 10% of patients with persistent symptoms lasting several weeks or more following acute infection. These COVID-19 “long haulers,” including cases ranging from mild to severe, have described a wide array of ongoing, unpredictable impairments in physical, cognitive, emotional, and occupational functioning.1 Many patients experience serious effects; for example, preliminary study results suggest that roughly two-thirds of patients incur organ damage. A group of clinicians in the United Kingdom with long COVID have reported new-onset diabetes, cardiovascular disease, and interstitial lung disease, among other effects and conditions, since the time of their infection. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Rehabilitation in the wake of Covid 19: a phoenix from the ashes Author(s): Dr Margaret Phillips, Prof Lynne Turner-Stokes, Prof Derick Wade, Dr Krystyna Walton, Dr Mike Dilley, Prof Diane Playford, Dr Stephen Ashford, Dr Chris Danbury, Craig Brown, Prof Sally Singh, Miss Naomi Davis Publisher or Source: British Society of Rehabilitation Medicine Type of Media: Medical Professional Education Media Originally for: Critical Care Physicians Country of Origin: United Kingdom of Great Britain and Northern Ireland (the) Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: Yes Description: This document sets out the BSRM’s recommendations for rehabilitation services for adults aged 16 years and over in the wake of the Covid-19 pandemic - in particular, the role of specialist rehabilitation to support patients with more complex rehabilitation needs. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Post-intensive Care Syndrome (PICS): Early Recognition and Evaluation Author(s): Patricia J Ohtake, PT, PhD, Alan Chong W. Lee, PT, PhD, DPT, CWS, GCS, Jim Smith, PT, DPT. Publisher or Source: APTA and Academy of Acute Care Physical Therapy Type of Media: One-Pager Media Originally for: General Public Country of Origin: United States Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: No Description: Over 80% of survivors of critical illness experience post-intensive care syndrome (PICS). PICS is a constellation of physical, cognitive and mental health problems after intensive care including prolonged muscle weakness, reduced performance of activities of daily living, diminished ambulation and strength, post-traumatic stress disorder, and anxiety that persists for months and years. PICS is a relatively recently described syndrome and many physical therapists in acute and sub-acute care, outpatient, and home care settings may not be familiar with the patient presentation, evaluation strategy, and interventions for these individuals. Using evidence from our recent systematic review, this session will characterize the physical impairments, activity limitations, and participation restrictions experienced by individuals with PICS during their first year following survival of an episode of critical illness. Strategies for outpatient clinic and home-based physical therapy examination and evaluation of this unique patient population will be discussed. Recent clinical trials of interventions for individuals with PICS aimed at reducing physical impairments and restoring functional activity and community participation will be presented. This course will conclude with a discussion of current challenges associated with the evaluation and physical therapy management of individuals with PICS and offer some potential solutions. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Considerations for the treatment of oesophageal cancer with radiotherapy during the COVID-19 pandemic Author(s): C.M. Jones, M. Hawkins, S. Mukherjee, G. Radhakrishna, T.Crosby Publisher or Source: Royal College of Radiologists Type of Media: Medical Journal Media Originally for: Critical Care Physicians,General Medical Professionals,Nurses and/or Other Critical Care Medical Professionals Country of Origin: United Kingdom of Great Britain and Northern Ireland (the) Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: Yes Description: Considerations for the treatment of oesophageal cancer with radiotherapy during the COVID-19 pandemic. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: What is long Covid and how can I tell if I’ve got it? Author(s): Press Association 2021 Publisher or Source: Swindon Advertiser Type of Media: Newspaper Article Media Originally for: General Public Country of Origin: United Kingdom of Great Britain and Northern Ireland (the) Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: More must be done to support people with long Covid and their loved ones, academics have said. Here, the PA news agency answers the key questions about the condition. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Cost and outcome of intensive care for patients with AIDS, Pneumocystis carinii pneumonia, and severe respiratory failure Author(s): Wachter R M, Luce J M, Safrin, S, Berrios D C, Charlebois E, Scitovsky A A Publisher or Source: University of York - by the Centre for Reviews and Dissemination Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: United Kingdom of Great Britain and Northern Ireland (the) Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Intensive care for patients with AIDS-related Pneumocystis carinii pneumonia and severe respiratory failure. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: After the Storm: UPMC’s Critical Illness Recovery Center Focuses on Post-Intensive Care Syndrome Author(s): Andy Mulkerin Publisher or Source: University of Pittsburgh Medical Center Type of Media: Newspaper Article Media Originally for: Critical Care Physicians, General Medical Professionals, Nurses and/or Other Critical Care Medical Professionals Country of Origin: United States Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: Early this year, when the world was first coming to grips with the spread of COVID-19 and the challenges it would present, Dr. Brad Butcher, a critical care medicine specialist at UPMC Mercy, was focused on what was coming next. “We heard that patients who required time in the intensive care unit, and particularly time on a mechanical ventilator, were staying on the ventilator for a very long time,” he said. “This is concerning because the longer people stay in bed, the more physical weakness can develop, and the longer they’re on ventilation, the more drugs they need to sedate them.” Additional medication increases the risk of patients developing delirium, which raises the likelihood of long-term cognitive complications from the critical illness. These conditions would only be intensified by the limited interactions with care providers and loved ones permitted by COVID-19 safety protocols. “We were very concerned that these patients would be at increased risk for anxiety, depression and post-traumatic stress disorder,” Butcher said. In other words, COVID-19 had the potential to create a perfect storm in the realm where Butcher and his colleague Tammy Eaton, C.R.N.P., specialize: Post-Intensive Care Syndrome (PICS). PICS is a set of conditions that have been around as long as critical care medicine, but it received a name only a decade ago. Addressing PICS is the mission of the UPMC Critical Illness Recovery Center (CIRC), which Butcher and Eaton founded at UPMC Mercy. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: A meta-analysis and systematic review of percutaneous catheter drainage in treating infected pancreatitis necrosis. Author(s): Zhang, Z. H., Ding, Y. X., Wu, Y. D., Gao, C. C., & Li, F. Publisher or Source: Medicine Type of Media: Medical Journal Media Originally for: Critical Care Physicians Country of Origin: China Primary Focus of Media: Pre-Use of PICS Designation COVID-19 Related: No Description: Background: In the current meta-analysis, we focus on the exploration of percutaneous catheter drainage (PCD) in terms of its overall safety as well as efficacy in the treatment of infected pancreatitis necrosis based on qualified studies. Methods: The following electronic databases were searched to identify eligible studies through the use of index words updated to May 2018: PubMed, Cochrane, and Embase. Relative risk (RR) or mean difference (MD) along with 95% confidence interval (95% CI) were utilized for the main outcomes. Results: A total of 622 patients in the PCD group and 650 patients in the control group from 13 studies were included in the present meta-analysis. The aggregated results indicated that the incidence of bleeding was decreased significantly (RR: 0.42, 95% CI: 0.25-0.70) in the PCD group as compared with the control group. In addition, PCD decreased the mortality (RR: 0.76, 95% CI: 0.41-1.42), hospital duration (SMD: -0.22, 95% CI: -0.77 to -0.33), duration in intensive care unit (ICU) (SMD: -0.13, 95% CI: -0.30 to -0.04), pancreatic fistula (RR: 0.73, 95% CI: 0.46-1.17), and organ failure (RR: 0.91, 95% CI: 0.45-1.82) in comparison with the control group, but without statistical significance. Conclusion: Our findings provide evidence for the treatment effect of PCD in the decrease of bleeding, mortality, duration in hospital and ICU, pancreatic fistula, organ failure as compared with the surgical treatment. In conclusion, further studies based on high-quality RCTs with larger sample size and long-term follow-ups are warranted for the confirmation of PCD efficacy in treating infected pancreatitis necrosis. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: ICU Stays Can Result in Long-Lasting Mental Health Problems Author(s): Sorgen, C. Publisher or Source: Psychiatry News Type of Media: Medical Journal Media Originally for: General Public,General Medical Professionals Country of Origin: United States of America (the) Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: No Description: Almost 6 million patients a year are admitted to an intensive care unit (ICU) in the United States, according to the Society of Critical Care Medicine (SCCM). The majority of those survive to be discharged. But for many of them, though their initial illness or injury may have been resolved, a new challenge awaits—a cluster of health problems commonly referred to as post-intensive care syndrome (PICS). To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

Click to Return to Search Page VIEW SELECTED LIBRARY MEDIA Name of Media: Medical professionals explain potential long-term impacts of COVID-19 Author(s): Luis de Leon Publisher or Source: KVUE.com Type of Media: Newspaper Article Media Originally for: General Public Country of Origin: United States of America (the) Primary Focus of Media: Post Intensive Care Syndrome (PICS) COVID-19 Related: Yes Description: AUSTIN, Texas — When someone is hospitalized for COVID-19, they may not need to be put on a ventilator. But doctors say even having to be hospitalized for the virus could potentially leave lasting health complications for a patient – even after they're discharged. Doctors say it's too early to fully understand what the exact common or rare long-term impacts of COVID-19 are, but some complications could arise. To view the PDF, Article, Photo, or Chart, Click Icon: To view the attached Video media file, Click Icon: PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.