Significant improvements have been made with regard to mortality in patients with sepsis and critical illness over the last decade. However, this success is mitigated by the fact that 60-80 % of critically ill patients will become delirious during their hospital stay1, 50-70% will suffer cognitive impairment after discharge,2 and 60-80% will have physical disability due to ICU acquired weakness3. Furthermore, survivors of critical illness are five times more likely to develop depression4 after discharge and up to 25% will experience symptoms of post-traumatic stress disorder (PTSD)5.