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Name of Media:

For adults with acute respiratory distress syndrome (ARDS) who are mechanically ventilated, how does immunonutrition compare with standard formula feeding?


Adarsh Gupta

Publisher or Source:

Cochrane Clinical Answers

Type of Media:

Medical Professional Education

Media Originally for:

Critical Care Physicians,Nurses and/or Other Critical Care Medical Professionals

Country of Origin:

United Kingdom of Great Britain and Northern Ireland (the)

Primary Focus of Media:

Pre-Use of PICS Designation

COVID-19 Related:



For adults with ARDS who are mechanically ventilated, very low‐certainty evidence suggests that immunonutrition may reduce intensive care unit days (by 3.09 days; all results on average) and ventilator days (by 2.24 days), and may lead to higher oxygenation (partial pressure of oxygen [PaO2]/fraction of inspired oxygen [FiO2] ratio difference of 38.88 mmHg) compared with standard formula feeding. Low‐ to very low‐certainty evidence suggests little to no difference in nosocomial infection between the two types of nutrition; effects on mortality and on the overall number of adverse events are uncertain due to imprecision of the results.

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