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Name of Media:

Effects of mindfulness training programmes delivered by a self-directed mobile app and by telephone compared with an education programme for survivors of critical illness: a pilot randomised clinical trial


Christopher Ecox, Catherine l Hough, Derek M Jones, Anna Ungar, Wen Reagan, Mary D Key, Tina Gremore, Maren K Olsen, Linda Sanders, Jeffrey M greeson, Laura S Porter

Publisher or Source:


Type of Media:

Medical Journal

Media Originally for:

Critical Care Physicians, General Medical Professionals, Nurses and/or Other Critical Care Medical Professionals

Country of Origin:

United States

Primary Focus of Media:

Post Traumatic Stress Disorder (PTSD)

COVID-19 Related:



Background: Patients who are sick enough to be admitted to an intensive care unit (ICU) commonly experience symptoms of psychological distress after discharge, yet few effective therapies have been applied to meet their needs.
Methods: Pilot randomised clinical trial with 3-month follow-up conducted at two academic medical centres. adult (≥18 years) icU patients treated for cardiorespiratory failure were randomised after discharge home to 1 of 3month-long interventions: a self-directed mobile app-based mindfulness programme; a therapist-led telephone-based mindfulness programme; or a web-based critical illness education programme.
Results: among 80 patients allocated to mobile mindfulness (n=31), telephone mindfulness (n=31) or education (n=18), 66 (83%) completed the study. For the primary outcomes, target benchmarks were exceeded by observed rates for all participants for feasibility (consent 74%, randomisation 91%, retention 83%), acceptability (mean client Satisfaction Questionnaire 27.6 (SD 3.8)) and usability (mean Systems Usability Score 89.1 (SD 11.5)). For secondary outcomes, mean values (and 95% cis) reflected clinically significant group-based changes on the Patient Health Questionnaire depression scale (mobile (−4.8 (−6.6, −2.9)), telephone (−3.9 (−5.6, −2.2)), education (−3.0 (−5.3, 0.8)); the generalized anxiety Disorder scale (mobile −2.1 (−3.7, −0.5), telephone −1.6 (−3.0, −0.1), education −0.6 (−2.5, 1.3)); the Post-traumatic Stress Scale (mobile −2.6 (−6.3, 1.2), telephone −2.2 (−5.6, 1.2), education −3.5 (−8.0, 1.0)); and the Patient Health Questionnaire physical symptom scale (mobile −5.3 (−7.0, −3.7), telephone −3.7 (−5.2, 2.2), education −4.8 (−6.8, 2.7)).
Conclusions: Among ICU patients, a mobile mindfulness app initiated after hospital discharge demonstrated evidence of feasibility, acceptability and usability and had a similar impact on psychological distress and physical symptoms as a therapist-led programme. a larger trial is warranted to formally test the efficacy of this approach.

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