top of page


Name of Media:

Mannitol versus hypertonic saline for brain relaxation in patients undergoing craniotomy


Prabhakar, H., Singh, G. P., Anand, V., & Kalaivani, M.

Publisher or Source:

Sao Paulo Medical Journal

Type of Media:

Medical Journal

Media Originally for:

Critical Care Physicians

Country of Origin:


Primary Focus of Media:

Pre-Use of PICS Designation

COVID-19 Related:




Patients with brain tumour usually suffer from increased pressure in the skull due to swelling of brain tissue. A swollen brain renders surgical removal of the brain tumour difficult. To ease surgical tumour removal, measures are taken to reduce brain swelling, often referred to as brain relaxation. Brain relaxation can be achieved with intravenous fluids such as mannitol or hypertonic saline. This review was conducted to find out which of the two fluids may have a greater impact on brain relaxation.


To compare the effects of mannitol versus those of hypertonic saline on intraoperative brain relaxation in patients undergoing craniotomy.

To view the attached Video media file, Click Icon:

PostICU, Inc's library staff reviewed this copyrighted material contained in the library and reasonably believes that its inclusion in our library complies with the "Fair Use Doctrine" because: (1) our library's is for nonprofit and educational purposes; (2) the nature of the copyrighted work is related to our mission; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole is fair and reasonable; and (4) the potential market for or value of the copyrighted work will if impacted, should be enhanced, by its presence in our library.

bottom of page